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Unlike Tobacco Smoke E-cig Vapor Does Not Cause DNA Mutations, Findings Show

dna_strandScientists at British American Tobacco (BAT) conducted lab-based tests observing the rate of mutation in DNA when exposed to smoke and vapor, and found that unlike smoke, vapor does not cause genetic mutations, which may be linked to cancer.

BAT is a multinational company headquartered in London, England and is one of the world’s largest tobacco companies. Scientists there used the Ames test, which allowed them to compare the mutagenic potential of cigarette smoke and vapor produced by the Vype ePen on DNA using test bacteria.

“To do this, they trapped particulate matter from smoke or vapor on a filter pad and then washed the pad with a solvent to produce a stock solution that could be diluted into various concentrations. They then exposed the test bacteria to the same concentrations of either smoke or vapor extract. They also exposed test bacteria to freshly generated smoke or e-cigarette vapor,” reads the article published in News Medical Life Sciences, a medical information service provider.

Smoke exposure caused mutations in the bacteria, and the higher the dose, the higher the mutation rate. Whereas e-cigarette vapor extracts left the bacteria unaffected, and did not cause any mutations whatsoever, according to News Medical Life Sciences.

“These findings suggest that Vype ePen vapor does not induce the mutations observed on exposure to smoke,” said Dr. James Murphy, Head of Reduced Risk Substantiation at BAT.

He added, “This study adds data to support the growing evidence base that e-cigarettes have the potential to be significantly less harmful compared to cigarette smoke, though more research is needed.”

To read more, click here for the News Medical Life Sciences article.